| 发明名称 |
PROTEINS PRODUCING AN ALTERED IMMUNOGENIC RESPONSE AND METHODS OF MAKING AND USING THE SAME |
| 摘要 |
The present invention relates to a novel methods and compositions for producing hyper and hypo allergenic compositions. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein. Alternatively, T-cell epitopes are mutated to produce increased immunogenic reactions. Moreover, naturally occurring proteins are provided.
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| 申请公布号 |
WO0159130(A2) |
申请公布日期 |
2001.08.16 |
| 申请号 |
WO2001US02204 |
申请日期 |
2001.01.22 |
| 申请人 |
GENENCOR INTERNATIONAL, INC. |
发明人 |
ESTELL, DAVID, A.;HARDING, FIONA, A. |
| 分类号 |
A23K1/165;A61K8/00;A61K8/64;A61K8/66;A61K8/72;A61K8/99;A61K38/00;A61K38/22;A61K38/43;A61K38/44;A61K38/45;A61K38/46;A61K38/52;A61K39/00;A61P31/00;A61P35/00;A61P37/02;A61P37/08;A61P43/00;A61Q5/02;A61Q11/00;A61Q19/10;C11D3/386;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/02;C12N9/04;C12N9/10;C12N9/12;C12N9/14;C12N9/16;C12N9/20;C12N9/24;C12N9/42;C12N9/54;C12N9/64;C12N9/90;C12N15/09;C12N15/55;C12N15/56;C12N15/57;C12N15/63;G01N33/50;G01N33/68;(IPC1-7):C12N15/55;C12N9/56;A61K38/47;A61K38/48;C12Q1/34;C12Q1/37 |
主分类号 |
A23K1/165 |
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