The present invention relates to methods for using a human protein kinase belonging to the superfamily of mammalian protein kinases. The invention also relates to methods for using polynucleotides encoding the protein kinase. The invention relates to methods using the protein kinase polypeptides and polynucleotides as a target for diagnosis and treatment in protein kinase-mediated or related disorders. The invention further relates to drug-screening methods using the protein kinase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the protein kinase polypeptides and polynucletides. The invention further relates to agonists and antagonists identified by drug screening methods with the protein kinase polypeptides and polynucleotides as a target.
申请公布号
WO0159081(A2)
申请公布日期
2001.08.16
申请号
WO2001US04281
申请日期
2001.02.09
申请人
MILLENNIUM PHARMACEUTICALS, INC.;GALVIN, KATHERINE, M.;KAPELLER-LIBERMANN, ROSANA;WEICH, NADINE, S.
发明人
GALVIN, KATHERINE, M.;KAPELLER-LIBERMANN, ROSANA;WEICH, NADINE, S.