发明名称 AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME
摘要 <p>Compounds of a formula: &lt;CHEM&gt; wherein Ring A represents an optionally-substituted aromatic ring; Ring B represents an optionally-substituted cyclic hydrocarbon group; Z represents an optionally-substituted cyclic group; R&lt;1&gt; represents a hydrogen atom, an optionally-substituted hydrocarbon group, an optionally-substituted heterocyclic group, or an acyl group; R&lt;2&gt; represents an optionally-substituted amino group; D represents a chemical bond or a divalent group; E represents -CO-, -CON(R&lt;a&gt;)-, COO-, -N(R&lt;a&gt;)CON(R&lt;b&gt;)-, -N(R&lt;a&gt;)COO-, -N(R&lt;a&gt;)SO2-, -N(R&lt;a&gt;)-, -O-, -S-,-SO- or -SO2- (in which R&lt;a&gt; and R&lt;b&gt; each independently represent a hydrogen atom or an optionally-substituted hydrocarbon group); G represents a chemical bond or a divalent group; L represents (1) a chemical bond or (2) a divalent hydrocarbon group optionally having from 1 to 5 substituents selected from; (i) a C1-6 alkyl group, (ii) a halogeno-C1-6 alkyl group, (iii) a phenyl group, (iv) a benzyl group, (v) an optionally-substituted amino group, (vi) an optionally-substituted hydroxy group, and (vii) a carbamoyl or thiocarbamoyl group optionally substituted by: &lt;1&gt; a C1-6 alkyl group, &lt;2&gt; an optionally-substituted phenyl group, or &lt;3&gt; an optionally-substituted heterocyclic group, and optionally interrupted by -O- or -S-; X represents an oxygen atom, an optionally-oxidized sulfur atom, an optionally-substituted nitrogen atom, or an optionally-substituted divalent hydrocarbon group; Y represents two hydrogen atoms, an oxygen atom or a sulfur atom; .... means that R&lt;2&gt; may be bonded to the atom on Ring B to form a ring, or their salts, and a method for producing them.</p>
申请公布号 EP1123918(A1) 申请公布日期 2001.08.16
申请号 EP19990947962 申请日期 1999.10.19
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 OI, SATORU;SUZUKI, NOBUHIRO;ASO, KAZUYOSHI;BANNO, YOSHIHIRO
分类号 A61P5/02;C07C233/06;C07C233/18;C07C233/25;C07C255/60;C07D207/26;C07D207/27;C07D209/08;C07D209/14;C07D211/62;C07D211/96;C07D213/40;C07D213/74;C07D213/75;C07D215/20;C07D217/04;C07D217/06;C07D221/20;C07D277/30;C07D277/74;C07D285/12;C07D285/125;C07D295/13;C07D295/185;C07D307/68;C07D307/81;C07D327/04;C07D333/20;C07D401/04;C07D405/12;C07D409/12;(IPC1-7):C07C231/12;C07C317/44;C07C235/00;C07C233/01;C07C311/00;C07C237/00 主分类号 A61P5/02
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