| 发明名称 |
INTERNAL 1,15-LACTONES OF FLUPROSTENOL AND RELATED PROSTAGLANDIN F2 alpha ANALOGS AND THEIR USE IN THE TREATMENT OF GLAUCOMA AND INTRAOCULAR HYPERTENSION |
| 摘要 |
<p>Novel derivatives of prostaglandin compounds of the F-series (PGF), specifically macrocyclic internal 1,15-lactones of fluprostenol and related PGF analogs, such as cloprostenol or latanoprost. The novel analogs can be formulated into ophthalmic solutions and topically applied for the treatment of the increased intraocular pressure caused by glaucoma and the reduction of ocular hypertension.</p> |
| 申请公布号 |
WO0157015(A1) |
申请公布日期 |
2001.08.09 |
| 申请号 |
WO2001US03559 |
申请日期 |
2001.02.01 |
| 申请人 |
CAYMAN CHEMICAL COMPANY, INC.;MAXEY, KIRK, M.;STANTON, MICHELLE, L. |
发明人 |
MAXEY, KIRK, M.;STANTON, MICHELLE, L. |
| 分类号 |
A61K9/08;A61K31/365;A61P27/02;A61P27/06;A61P43/00;C07C405/00;C07D267/00;C07D313/00;C07D321/00;C07D327/02;(IPC1-7):C07D313/00 |
主分类号 |
A61K9/08 |
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