发明名称 HYPERTHERMIA AND IMMUNOTHERAPY FOR LEUKEMIAS, LYMPHOMAS, AND SOLID TUMORS
摘要 An improved method of inducing whole-body hyperthermia and enhanced anti-tumor immune response through inoculation of a fever virus with nil mortality and subsequent injection of irradiated tumor cells derived from the patient. This therapy will safely reduce the tumor burden by 90-99.9% by physical means (fever), before raising intererferon levels to over 250 times baseline. The Activated Lymphokine Killer cells produced by these high interferon levels are capable of killing any cell expressing viral or tumor antigens, even those which had previously escaped immune surveillance. As a fin final step in the process, a specific class of Cytotoxic T Lymphocytes programmed to destroy the patient's own cancer cells will be produced by repeated inoculation of dendritic cells harvested from the patient. Through a combination of three methods never previously integrated into a single regimen, it is logical to state that this therapy has a high probability of completely eradicating cancer cells from the patient. In addition, this therapy provides for life-long immunity to the reoccurrence of the disease.
申请公布号 WO0156599(A2) 申请公布日期 2001.08.09
申请号 WO2001US03565 申请日期 2001.02.02
申请人 TRIAD IMMUNOLOGIES, LLC 发明人 LYDAY, BRUCE, W.
分类号 A61K35/76;A61K35/12;A61K39/00;A61K39/39;A61P35/00;C12N7/02;(IPC1-7):A61K39/12 主分类号 A61K35/76
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