INHIBITORS OF FACTOR Xa

摘要

Compounds of the formula A - Y - D - E - G - J - Z - L in which D is a direct link, a substituted or unsubstituted phenyl or naphtyl group or a heterocyclic ring system; Z is a substituted or unsubstituted phenyl or naphthyl group or a heterocyclic ring system; and the other variables are as defined in the claims, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.