发明名称 |
LIGAND FOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR |
摘要 |
The present invention relates to compositions comprised of a peptide ligand or derivatives thereof that are capable of specific binding to the high affinity receptor-1 of vascular endothelial growth factor (VEGF) and structure similar receptors. The invention further provides a peptide ligand or derivatives thereof that are capable of inhibiting angiogenesis induced by VEGF. The present invention also provides a method for treatment or diagnosis of disease associated with angiogenesis in a patient in need of therapy comprising administering to the patient an effective amount of the pharmaceutical composition of the present invention and a pharmaceutical acceptable carrier.
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申请公布号 |
WO0157067(A1) |
申请公布日期 |
2001.08.09 |
申请号 |
WO2001IB00135 |
申请日期 |
2001.02.02 |
申请人 |
SUPRATEK PHARMA INC. |
发明人 |
TCHISTIAKOVA, LIOUDMILA;LI, SHENGMIN;PIETRZYNSKI, GRZEGORZ;ALAKHOV, VALERY |
分类号 |
C12N15/09;A61K38/00;A61K48/00;A61P7/02;A61P9/00;A61P9/10;A61P9/14;A61P11/00;A61P17/02;A61P17/06;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07K7/08;C07K14/52;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C40B40/02;C40B50/06;(IPC1-7):C07K4/12;A61K38/03;A61K38/10;C12N15/11 |
主分类号 |
C12N15/09 |
代理机构 |
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