| 发明名称 |
Enzymatic acylation of a retinol derivative |
| 摘要 |
Preparation of (11Z, 13Z)-7,10-dihydro-10-hydroxy retinylacyl derivatives of formula (I) comprises selective monoacylation of compounds of formula (II) in organic solvents with an acylating agent in the presence of a suspended lipase. R = 1-23C alkyl or 1-3 double bond containing 2-23C alkenyl. |
| 申请公布号 |
EP0802261(B1) |
申请公布日期 |
2001.08.08 |
| 申请号 |
EP19970105918 |
申请日期 |
1997.04.10 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
ORSAT, BERNARD;SPURR, PAUL;WIRZ, BEAT |
| 分类号 |
C12N9/20;C07C35/18;C12P7/40;C12P7/62;C12P7/64;C12P23/00;(IPC1-7):C12P23/00 |
主分类号 |
C12N9/20 |
| 代理机构 |
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