SURFACTANT FREE TOPICAL COMPOSITIONS AND METHOD FOR RAPID PREPARATION THEREOF

摘要

The present invention relates to a composition for topical, oral, nasal, anal, ophthalmic, or vaginal application comprising a base composition and at least one dispersion comprising suspended particles of a hydrophobic active agent, a hydrophobic adjuvant, or a combination thereof. The base composition comprises a rheology modifying agent and water. The composition is substantially free of emulsifying surfactants and the suspended particles generally have a diameter less than about 500 or 1,000 nm. Another embodiment is a method of preparing a composition comprising mixing the aforementioned base composition with the aforementioned dispersion. Mixing may be performed with a propeller mixer or manually, i.e., by hand. Since the topical dispersion is simple and quick to prepare, custom cosmetic compositions may be prepared at the point of sale for customers. Prior to the present invention, such products would take hours to be prepared. Furthermore, the method of the present invention is significantly more efficient i.e less expensive and faster) than conventional methods for preparing emulsion-based compositions. The present invention further relates to a method of treating topical, oral, nasal, anal, ophthalmic or vaginal disorders with the composition of this invention.