<i>IN VITRO</i> SELECTION AND OPTIONAL IDENTIFICATION OF POLYPEPTIDES USING SOLID SUPPORT CARRIERS

摘要

The present invention relates to a method for the selection of one or more desired polypeptides comprising: (a) cell free expression of nucleic acid molecules immobilized on a solid support system to produce polypeptides, the solid support carrying means for biospecific interaction with at least the desired polypeptide or a molecule attached thereto; (b) separation of the solid support carrying both the desired polypeptide and the nucleic acid encoding it; and optionally (c) recovery of the said nucleic acid and/or said desired polypeptide; and molecular libraries for use in such methods.