发明名称 Method for sealing dentinal tubules through the in-situ formation of low-solubility precipitates
摘要 It was found that the combination of an alkaline earth or other cation , together with a suitable anion , when applied simultaneously -in vivo or in-vitro - slowly form microcrystalline deposits which block the tubuli of dentine and lower the pain caused by dentinal sensitivity. The data presented consist of scanning electron microscopic images, which indicate the mechanism by which the pain may be lowered , and clinical results obtained in a pilot trial using strontium as the cation and sodium fluorophosphates as a source for the anions fluoride and phosphate , demonstrating the validity of the in-vitro findings.
申请公布号 EP1120106(A1) 申请公布日期 2001.08.01
申请号 EP20000101251 申请日期 2000.01.25
申请人 NEIRINCKX, RUDI DOMINIQUE, DR. 发明人 NEIRINCKX, RUDI DOMINIQUE, DR.
分类号 A61K8/19;A61K8/21;A61Q11/00;(IPC1-7):A61K7/16;A61K7/18 主分类号 A61K8/19
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