发明名称 Method for enhancing the presentation of exogenous antigen by human antigen-presenting cells and opsonized micro particle complexes for applying this method
摘要 The invention relates to an opsonized micro-particle complex comprising : a micro-particular vector encapsulating at least one antigen and at least one antibody or fragment thereof, with said antibody being a human or humanized antibody or an antibody binding to human FcR with substantially the same affinity and avidity as the ones of a human antibody and with said antibody or fragment thereof having the carboxy terminal end of its Fc portion external with respect to the opsonized micro particle complex.
申请公布号 AU3161301(A) 申请公布日期 2001.07.31
申请号 AU20010031613 申请日期 2000.12.20
申请人 I.D.M. IMMUNO-DESIGNED MOLECULES;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE C.N.R.S. 发明人 LEE LESERMAN;ALESSANDRA NARDIN;JEAN-PIERRE ABASTADO;JACQUES BARTHOLEYNS;PATRICK MACHY;KARINE SERRE
分类号 A61K39/00;A61K39/145;A61K47/48;A61P31/00;A61P35/00;A61P37/04;C07K16/00;C07K16/28 主分类号 A61K39/00
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