发明名称 |
Method for enhancing the presentation of exogenous antigen by human antigen-presenting cells and opsonized micro particle complexes for applying this method |
摘要 |
The invention relates to an opsonized micro-particle complex comprising : a micro-particular vector encapsulating at least one antigen and at least one antibody or fragment thereof, with said antibody being a human or humanized antibody or an antibody binding to human FcR with substantially the same affinity and avidity as the ones of a human antibody and with said antibody or fragment thereof having the carboxy terminal end of its Fc portion external with respect to the opsonized micro particle complex. |
申请公布号 |
AU3161301(A) |
申请公布日期 |
2001.07.31 |
申请号 |
AU20010031613 |
申请日期 |
2000.12.20 |
申请人 |
I.D.M. IMMUNO-DESIGNED MOLECULES;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE C.N.R.S. |
发明人 |
LEE LESERMAN;ALESSANDRA NARDIN;JEAN-PIERRE ABASTADO;JACQUES BARTHOLEYNS;PATRICK MACHY;KARINE SERRE |
分类号 |
A61K39/00;A61K39/145;A61K47/48;A61P31/00;A61P35/00;A61P37/04;C07K16/00;C07K16/28 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|