发明名称 |
OUTER MEMBRANE VESICLE (OMV) VACCINE COMPRISING N. MENINGITIDIS SEROGROUP B OUTER MEMBRANE PROTEINS |
摘要 |
A composition comprising (a) <i>Neisseria meningitidis </i> serogroup B outer membrane vesicles (OMVs), and (b) an immunogenic component selected from other <i>Neisseria</i> proteins, or immunogenic fragments thereof. Component (b) preferably includes a protein from a different NmB strain from that from which the OMV of component (a) is derived. The OMVs are preferably obtained by deoxycholate extraction. Optionally, the composition may also comprise a protective antigen against other pathogens. |
申请公布号 |
WO0152885(A1) |
申请公布日期 |
2001.07.26 |
申请号 |
WO2001IB00166 |
申请日期 |
2001.01.17 |
申请人 |
CHIRON SPA;PIZZA, MARIAGRAZIA;RAPPUOLI, RINO;GIULIANI, MARZIA |
发明人 |
PIZZA, MARIAGRAZIA;RAPPUOLI, RINO;GIULIANI, MARZIA |
分类号 |
A61K39/02;A61K39/05;A61K39/08;A61K39/095;A61K39/10;A61K39/102;A61K39/106;A61K39/116;A61K39/13;A61K39/29;A61K39/295;A61K39/39;A61P25/00;A61P29/00;A61P31/04 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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