LOCAL DRUG DELIVERY USING PHOTOSENSITIZER-MEDIATED AND ELECTROMAGNETIC RADIATION-ENHANCED VASCULAR PERMEABILITY

摘要

The invention relates to the site specific delivery of drugs in an organism. The described methods facilitate the delivery of a therapeutic or diagnostic drug by increasing vascular permeability in a site specific manner. Vascular permeability is enhanced in the disclosed methods by using a combination of a photosensitizer and radiation applied to a site of interest.