发明名称 |
MATRIX TYPED ALGESIC ANTI-INFLAMMATORY AGENT FOR TRANSDERMAL ADMINISTRATION CONTAINING DICLOFENAC |
摘要 |
PURPOSE: A matrix typed algesic anti-inflammatory agent for transdermal administration containing Diclofenac is provided, thereby improving its skin-penetration and adhesion and decreasing time for its producing. CONSTITUTION: The matrix typed algesic anti-inflammatory agent for transdermal administration comprises a backing film which protects a drug; a matrix film containing an active drug; and a release liner film which is removed from the agent prior to using, in which the matrix film contains 1 to 25 wt.% of Diclofenac diethylammonium salt; 40 to 95 wt.% of water-insoluble acryl macromolecule as an adhesive component; 0.1 to 20 wt.% of nonionic surfactant selected from glyceryl monooleate, glyceryl monolaurate and sorbitan monooleate; 0.1 to 10 wt.% of menthol; and 0.1 to 10 wt.% of dissolution assistant selected from triacetin, isopropyl alcohol and propylene glycol, in which the water-insoluble acryl macromolecule is a monopolymer or a copolymer selected from 2-ethylhexyl acrylate, vinyl acrylate and vinyl acrylic acid. |
申请公布号 |
KR100305216(B1) |
申请公布日期 |
2001.07.26 |
申请号 |
KR19980036559 |
申请日期 |
1998.09.04 |
申请人 |
SAMYANG CORPORATION |
发明人 |
CHOI, YEONG GWON;LEE, HEON HAN;PARK, CHEOL MIN;SIM, YONG HO;SONG, JIN DEOK;YOON, HYE JEONG |
分类号 |
A61K9/70;(IPC1-7):A61K9/70 |
主分类号 |
A61K9/70 |
代理机构 |
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