发明名称 TETRAZOLE COMPOUNDS AS THYROID RECEPTOR LIGANDS
摘要 The present invention relates to tetrazole compounds of Formula I, stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, and pharmaceutically acceptable salts of the prodrugs. (see formula I) The invention also relates to compositions comprising the tetrazole compound s and to methods of treating obesity, diabetes, atherosclerosis, hypertension, corona ry heart disease, hypercholesterolemia, hyperlipidemia, thyroid disease, thyroid cancer, hypothyroidism, depression, glaucoma, cardiac arrhythmias, congestive heart failure, and osteoporosis using the tetrazole compounds.
申请公布号 CA2332066(A1) 申请公布日期 2001.07.25
申请号 CA20012332066 申请日期 2001.01.23
申请人 PFIZER PRODUCTS INC. 发明人 CHIANG, YUAN-CHING PHOEBE;ASPNES, GARY ERIK
分类号 C07D401/12;A61K31/41;A61K31/4427;A61K31/454;A61P3/04;A61P3/06;A61P3/10;A61P5/14;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P19/10;A61P25/24;A61P27/06;A61P35/00;A61P43/00;C07D257/04;C07D257/06;(IPC1-7):C07D257/04;C07D401/00;C07D403/00;C07D405/00;C07D409/00;C07D413/00;C07D417/00;C07D473/00;C07D475/00;A61P9/00;C07D471/04;C07D491/052;A61K31/437;A61K31/443;A61K31/470;A61K31/495;A61K31/53;A61K31/535;A61K31/541 主分类号 C07D401/12
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