CALCITONIN DERIVATIVE SUBSTITUTED AT 3 AND 26 POSITIONS

摘要

PROBLEM TO BE SOLVED: To provide a calcitonin or elkcatonin derivative having blood calcium density-lowering action and applicable in the field of medicaments. SOLUTION: This calcitonin or elkcatonin derivative substituted at the 3 position with asparagine residue having N-acetyl-D-glucosamine combined with nitrogen atom of side chain amide group and also substituted at the 26 position with asparagine residue having N-acetyl-D-glucosamine combined with nitrogen atom of side chain amide group is provided.