发明名称 METHOD OF PREPARING VACCINE BCG-M FOR SPARING PRIMARY IMMUNIZATION
摘要 medicine. SUBSTANCE: bacterial mass of culture BCG-M grown in solid potato medium and then in liquid synthetic media is removed, filtered, washed out with drying medium, ground in shuttle-apparatus to obtain homogeneous mass, diluted with stabilizing agent to prepare suspension containing 50 mg of BCG/1 ml followed by centrifugation at 2 000 rev/min for 15-20 min. Then supernatant suspension is diluted again to the final concentration 0.5 mg BCG/1 ml. Vaccine is ampouled and lyophilized. EFFECT: enhanced viability in single vaccinating dose. 1 cl, 3 tbl, 1 ex
申请公布号 RU2170588(C1) 申请公布日期 2001.07.20
申请号 RU20000104079 申请日期 2000.02.22
申请人 PREDPRIJATIE PO PROIZVODSTVU BAKTERIJNYKH PREPARATOV NAUCHNO-ISSLEDOVATEL'SKOGO INSTITUTA EHPIDEMIOL;PRED PROIZV BAKTERIJNYKH PREPA 发明人 NESTERENKO L.A.
分类号 A61K39/04;(IPC1-7):A61K39/04 主分类号 A61K39/04
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