发明名称 |
IMPROVED INTERSTITIAL FLUID MONITORING |
摘要 |
The present invention provides an improved method of measuring analytes in body fluids without the use of a sharp. The method having the steps of irradiating the skin of a patient by focused pulses of electromagnetic energy emitted by a laser. By proper selection of wavelength, energy fluence, pulse temporal width and irradiation spot size, the pulses precisely irradiate the skin to a selectable depth, without causing clinically relevant damage to healthy portions of the skin. After irradiation, interstitial fluid is collected into a container or left on the skin. The interstitial fluid is then tested for a desired analyte to approximate the analyte concentration in other body fluids. Alternatively, after the forced formation of a microblister, the epidermis covering the microblister is lysed and the interstitial fluid is subsequently collected and tested. |
申请公布号 |
WO0150970(A1) |
申请公布日期 |
2001.07.19 |
申请号 |
WO2000US00537 |
申请日期 |
2000.01.10 |
申请人 |
TRANSMEDICA INTERNATIONAL, INC. |
发明人 |
MARCHITTO, KEVIN, S.;FLOCK, STEPHEN, T. |
分类号 |
A61B10/00;A61B17/00;A61B18/20 |
主分类号 |
A61B10/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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