NOVEL PROCESS FOR THE PREPARATION OF .ALPHA.-(2-4-DISULFOPHENYL)-N-TERT-BUTYLNITRONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
摘要
A process for the preparation of .alpha.-(2-4-disulfophenyl)-N-tert- butylnitrone and pharmaceutically acceptable salts thereof by the reaction o f the corresponding disulfophenyl aldehyde with N-tert-butylhydroxylammonium acetate is disclosed.
申请公布号
CA2395971(A1)
申请公布日期
2001.07.19
申请号
CA20012395971
申请日期
2001.01.04
申请人
ASTRAZENECA AB;CENTAUR PHARMACEUTICALS, INC.
发明人
VAJDA, JOHN;MCGINLEY, JOHN;POUHOV, SERGEI;BLIXT, JORGEN;KRUK, HENRY