Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery with Taurolidine or Taurultam

摘要

The invention provides a method of reducing postoperative complications of cardiopulmonary bypass (CPB) surgery in which an effective amount of a methylol transfer agent, such as taurolidine, is administered to a patient in conjunction with CPB surgery. Patients undergoing crystalloid cardioplegia who were treated with taurolidine showed reduced levels of IL-6 and increased levels of IL-10 when compared to crystalloid patients administered a placebo.