Methods and apparatus for packing chromatography columns

摘要

Particulate chromatography medium such as silica is packed into a chromatography column (2) along a feed conduit (16,18) leading to a packing port (1) through the column wall. A motive flow of a liquid packing vehicle such as a non-polar organic solvent is established along a feed conduit by a pump (111). The medium, for example silica which is poorly compatible with low-polarity vehicles, is easily entrained in the motive flow by introducing it into the feed conduit (16,18) via an ejector (30). This avoids subjecting the medium to the action of a mechanical pump.