NICKEL-BASED REAGENTS FOR DETECTING DNA AND DNA-PROTEIN CONTACTS
摘要
The invention relates to a compound comprising a labeled nickel complex (Figure 1) that is used to detect and purify nucleic acid sequences by forming an adduct between a specific nucleic acid base and the labeled nickel complex. The adduct can also be purified through a separation process, such as affinity chromatography.
申请公布号
WO0102370(A9)
申请公布日期
2001.07.12
申请号
WO2000US18325
申请日期
2000.07.03
申请人
UNIVERSITY OF MARYLAND, COLLEGE PARK;UNIVERSITY OF UTAH;ROKITA, STEVEN, E.;BURROWS, CYNTHIA, J.
