发明名称 |
A novel isoform of human camp-dependent protein kinase, calpha-s, localizes to sperm midpiece and the use thereof |
摘要 |
The cloning of a novel human Calpha isoform, identified as the human Calpha-s protein on the basis of its similarity to a recently characterized Calpha isoform which was identified by purification and peptide sequencing of Calpha from ovine sperm. The human Calpha-s protein was present in testis and ejaculated sperm and Calpha-s localized to the midpiece of human sperm. A cDNA sequence encodes a Calpha-s protein and includes the specific nucleotide sequence shown in SEQ ID NO:1, wherein the protein is a new splice variant of Calpha catalytic subunit of cAMP dependent protein kinase. |
申请公布号 |
AU3063101(A) |
申请公布日期 |
2001.07.09 |
申请号 |
AU20010030631 |
申请日期 |
2000.12.21 |
申请人 |
NILS REINTON;KJETIL TASKEN;TRINE HAUGEN;SIGURD ORSTAVIK;TORE JAHNSEN;BJORN S. SKALHEGG |
发明人 |
NILS REINTON;SIGURD ORSTAVIK;TORE JAHNSEN;BJORN S. SKALHEGG;KJETIL TASKEN;TRINE HAUGEN |
分类号 |
G01N33/50;A61K31/711;A61K38/00;A61K38/45;A61K48/00;A61P15/08;A61P15/16;C12N9/12;C12N15/09;G01N33/15;G01N33/53;G01N33/573 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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