CELLS CAPABLE OF DIFFERENTIATING INTO HEART MUSCLE CELLS

摘要

Methods of isolating, purifying, culturing and differentiation-inducing cells which are capable of differentiating into heart muscle cells; a method of proliferating cells which are capable of differentiating into heart muscle cells and a method of regulating the differentiation thereof into heart muscle cells by using various cytokines, transcriptional factors, etc.; a method of acquiring a surface antigen specific to cells which are capable of differentiating into heart muscle cells; a method of acquiring a gene encoding this surface antigen; a method of acquiring an antibody specific to the above surface antigen; a method of acquiring a protein and a gene participating in the proliferation of cells which are capable of differentiating into heart muscle cells and differentiation thereof into heart muscle cells; remedies for various heart diseases with the use of cells which are capable of differentiating into heart muscle cells; and a method of inducing the differentiation of various cells (nerve cells, liver cells, fat cells, skeletal muscle cells, vascular endothelial cells, osteoblasts, etc.) and tissues by using cells which are capable of differentiating into heart muscle cells.