COMPOSITION FOR RESTORING DEFECTS IN CALCIFIED TISSUES
摘要
A composition for restoring defects in calcified tissues comprises an amorphous bioactive particulate consisting essentially of calcium, silicon and oxygen. Said agent may be selected from the group consisting of : a) a reaction product of an organic silicate source and a source of calcium; b) a calcium containing hydrolysis product of tetraethylorthosilicate; c) a calcium containing silica sol-gel; d) a binary calcium oxide and silicate precipitated material; e) a synthetic analog of a naturally occurring wollastonite-like calcium silicate; and f) a precipitated reaction product of soluble calcium source and a silicate solution. A process for producing the amorphous bioactive particulate consists essentially of adding a sufficient amount of a solution of a soluble calcium source to a solution of a silicate or silicate precursor to cause a precipitation of calcium-containing silicate particulate.
申请公布号
WO0110392(A3)
申请公布日期
2001.07.05
申请号
WO2000GB03015
申请日期
2000.08.04
申请人
BLOCK DRUG COMPANY, INC.;WHALLEY, KEVIN
发明人
DODD, GREGORY, P.;HALECKY, ALAN, A.;MARKOWITZ, KENNETH, J.