发明名称 Amphiphile Polyamine, deren Anwendungen und Verfahren zu ihrer Synthese
摘要 The invention relates to amphiphilc amines and the salts thereof, which may complex with biopolymers such as DNA, RNA, anti-sense oligonucleotides, ribozymes, proteins and peptides and transfer them into eucaryotic cells. Polyaminochinoline derivatives, which are modified with lipophilic groups are a particularly suited substance class. According to the invention, due to the property of forming aggregates with biologically active molecules such as, for example, DNA or RNA, said compounds are particularly suitable for use in gene therapy and, equally, for diagnostic purposes.
申请公布号 DE19960924(A1) 申请公布日期 2001.07.05
申请号 DE19991060924 申请日期 1999.12.17
申请人 KEIL, OLIVER 发明人 KEIL, OLIVER
分类号 A61K9/127;A61K31/7105;A61K31/711;A61K38/00;A61K45/00;A61K47/22;A61K47/24;A61K47/26;A61K47/28;A61K47/34;A61K47/48;A61K48/00;C07D215/46;C07J9/00;C12N15/88;(IPC1-7):C07D215/42;C12N15/00 主分类号 A61K9/127
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