| 发明名称 |
TEMPERATURE-SENSITIVE AND COLD-ADAPTED HUMAN PARAINFLUENZA VIRUS TYPE 2 (HPIV-2) AND VACCINES BASED ON SUCH VIRUS |
| 摘要 |
<p>The present invention relates to isolated, attenuated viral strains of human parainfluenza virus 2 (HPIV-2), which are useful in live vaccine preparations. These strains exhibit a temperature sensitive and cold adapted phenotype useful for stimulating a protective immune response in an inoculated mammal without producing severe symptoms.</p> |
| 申请公布号 |
EP1112350(A2) |
申请公布日期 |
2001.07.04 |
| 申请号 |
EP19990945354 |
申请日期 |
1999.08.31 |
| 申请人 |
ST. LOUIS UNIVERSITY |
发明人 |
BELSHE, ROBERT, B.;NEWMAN, FRANCES, K. |
| 分类号 |
C12N7/04;A61K39/145;A61K39/155;A61K39/39;A61P31/16;C12N7/08;C12R1/92;(IPC1-7):C12N7/08 |
主分类号 |
C12N7/04 |
| 代理机构 |
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