发明名称 Nitro-benzamide useful as anti-arrhythmic agent
摘要 Hydrated N-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-4-nitro benzamide hydrochloride characterised in that it: (i) comprises water in the range of from 1.7 to 2.4 molar equivalents; and/or (ii) has a melting point above 145 DEG C and/or, (iii) provides an infra red spectrum containing peaks at 3510, 3342, 3076, 1665, 1598, 1343, 1330, 1216 and 801 cm-1; and/or (iv) provides a solid state nuclear magnetic resonance spectrum containing chemical shifts substantially as represented in Table I; and/or (v) provides an X-ray powder refraction (XRPD) pattern substantially as represented in Table II; a process for preparing such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine.
申请公布号 NZ337794(A) 申请公布日期 2001.06.29
申请号 NZ19980337794 申请日期 1998.03.24
申请人 SMITHKLINE BEECHAM P 发明人 SLATER, GRAHAM RALPH;WESTLAKE, PAUL JEFFREY
分类号 A61P9/06;A61K31/166;C07C233/78;(IPC1-7):C07C233/78;A61K31/165 主分类号 A61P9/06
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