发明名称 Substituted cyclic amino acids as pharmaceutical agents
摘要 A compound of formula I, a pharmaceutically acceptable salt thereof or a prodrug thereof wherein, R1 to R10 are each independently selected from straight or branched alkyl of from 1 to 6 carbon atoms, unsubstituted or substituted benzyl or phenyl which substituents are selected from halogen, alkyl, alkoxy, hydroxy, carboxy, carboalkoxy, trifluoromethyl, and nitro, and any R1 to R10, which is not one of the above, is hydrogen, provided that R1 to R10 are not all hydrogen. Pharmaceutical compositions comprising the aforementioned compounds are also described as is the use of these compounds in the manufacture of medicaments for the treatment of a variety of disorders including: epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain and neuropathological disorders.
申请公布号 NZ331143(A) 申请公布日期 2001.06.29
申请号 NZ19970331143 申请日期 1997.02.18
申请人 WARNER-LAMBERT COMPANY 发明人 HORWELL, DAVID CHRISTOPHER;BRYANS, JUSTIN S;KNEEN, CLARE O;MORRELL, ANDREW I;RATCLIFFE, GILES S;HARTENSTEIN, JOHANNES
分类号 A61K31/195;A61K31/00;A61P25/08;A61P25/12;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;C07C229/28;C07C233/47;(IPC1-7):C07C229/28;A61K31/16 主分类号 A61K31/195
代理机构 代理人
主权项
地址