The present invention relates to a new family of sterol sensing domain proteins which modulate the release of Hedgehog proteins and lipid modified hydrophobic proteins from cells. Such proteins e.g. are involved in developmental processes, differentiation, regeneration and cell homeostasis, making them particularly suitable tools for diagnosis and therapy.
申请公布号
WO0146227(A2)
申请公布日期
2001.06.28
申请号
WO2000CH00672
申请日期
2000.12.19
申请人
UNIVERSITY OF ZURICH;BURKE, RICHARD, EDWARD;BASLER, KONRAD