发明名称 METHODS FOR LOWERING PLATELET COUNT.
摘要 1. The method for lowering human platelet count comprising administering to said human in need an effective amount of a compound of formula I wherein R<1> and R<3> are, independently, -H, -CH3, -CO(C1-C6 alkyl), or -COAr, where Ar is optionally substituted phenyl; R<2> is selected from the group consisting of pyrrolidine, piperidine, and hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof. 2. A method according to Claim 1 wherein said compound is [2-(4-hydroxyphenyl)-6-hydroxybenzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride. 3. A method according to Claim 1 wherein said human is a post-menopausal women. 4. A method according to Claim 3 wherein said compound is administered in an amount of 60 mg/day via the oral route.
申请公布号 EA001582(B1) 申请公布日期 2001.06.25
申请号 EA20000000243 申请日期 1998.08.17
申请人 ELI LILLY AND COMPANY 发明人 LAKSHMANAN, MARK, CHANDRAKANT
分类号 C07D333/56;A61K31/4025;A61K31/4535;A61K31/55;A61P7/00 主分类号 C07D333/56
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