摘要 |
<p>Compounds of general formula (1), prodrugs of the same, or pharmaceutically acceptable salts of both are useful as preventive or therapeutic drugs for disease due to increased sodium/proton exchange: (1) wherein R is an optionally substituted benzene ring, a fused polycyclic carbo-ring which may be substituted, an optionally substituted monocyclic hetero-ring, or an optionally substituted polycyclic hetero-ring; A and E are each independently a single bond, lower alkylene, or the like; G is a single bond, oxygen, or the like; and Y is -SO3H or the like.</p> |