A pseudomycin prodrug represented by structure (A) where R1 is a phosphate benzyloxycarbamate or phosphate methyleneoxycarbamate linkage is described. The phosphate prodrug demonstrates antifungal activity with less adverse side effects than the parent pseudomycin compound.
申请公布号
WO0141534(A2)
申请公布日期
2001.06.14
申请号
WO2000US30167
申请日期
2000.11.29
申请人
ELI LILLY AND COMPANY;CHEN, SHU, HUI;SUN, XICHENG, DAVID;ZHANG, YANZHI