| 发明名称 |
METHOD FOR THE PREVENTION AND/OR TREATMENT OF ATHEROSCLEROSIS |
| 摘要 |
The instant invention provides a method for raising serum HDL cholesterol levels comprising administering a therapeutically effective amount of an LXR ligand to a patient in need of such treatment. It further provides a method for using an LXR ligand to stimulate expression of the ABC1 gene. LXR ligand s can be used for preventing and treating atherosclerosis and related conditio ns. |
| 申请公布号 |
CA2392568(A1) |
申请公布日期 |
2001.06.14 |
| 申请号 |
CA20002392568 |
申请日期 |
2000.12.07 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
SPARROW, CARL P.;ONDEYKA, JOHN G.;SINGH, SHEO BUX |
| 分类号 |
A61K45/00;A61K31/222;A61K38/17;A61K48/00;A61P9/10;A61P15/10;A61P25/28;A61P43/00;C07C69/16;(IPC1-7):A61K31/21;A61K31/19;A61K31/35 |
主分类号 |
A61K45/00 |
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