发明名称 |
Heterocyclic dihydropyrimidines as potassium channel inhibitors |
摘要 |
Novel heterocyclic dihydropyrimidine compounds useful as inhibitors of potassium channel function (especially inhibitors of the Kv1 subfamily of voltage gated K+ channels, especially inhibitors Kv1.5 which has been linked to the ultra-rapidly activating delayed rectifier K+ current IKur), methods of using such compounds in the prevention and treatment of arrhythmia and IKur-associated conditions, and pharmaceutical compositions containing such compounds. |
申请公布号 |
AU1812701(A) |
申请公布日期 |
2001.06.12 |
申请号 |
AU20010018127 |
申请日期 |
2000.12.04 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
KARNAIL S. ATWAL;WAYNE VACCARO;JOHN LLOYD;HEATHER FINLAY;LIN YAN;RAO S. BHANDARU |
分类号 |
A61K31/519;A61K31/55;A61K45/00;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P3/06;A61P3/10;A61P5/14;A61P7/02;A61P7/06;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P17/08;A61P17/14;A61P19/02;A61P19/10;A61P21/00;A61P21/04;A61P25/06;A61P25/08;A61P25/16;A61P25/28;A61P27/02;A61P27/12;A61P27/16;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P31/22;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D487/04;C07D519/00 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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