发明名称 SOLID PREPARATION
摘要 The present invention provides a solid preparation comprising a crystal of [ 3- [(2R)-[[(2R)-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1H-indol-7- yloxy]acetic acid (Compound A), especially a crystal of Compound A having a particle size of not larger than 100 .mu.m at the cumulative weight distribution value of 50 %, and not larger than 200 .mu.m at the cumulative weight distribution value of 95 %, preferably a solid preparation having the excellent stability and the content uniformity of Compound A, which is prepared by preparing granules of the crystal of Compound A with fillers, disintegrants and binders, and then followed by mixing said granules with external excipients.
申请公布号 CA2391646(A1) 申请公布日期 2001.06.07
申请号 CA20002391646 申请日期 2000.11.24
申请人 DAINIPPON PHARMACEUTICAL CO., LTD. 发明人 FUJITA, MEGUMI;KURIYAMA, TERUAKI;IWATA, MOTOKAZU;ODAI, OSAMU;KAWASHIMA, HITOSHI;FUJII, AKIHITO;HARADA, HIROSHI;FUJIWARA, KEIICHI;KATO, SHIRO
分类号 A61K9/14;A61K9/20;A61K31/404;A61P3/04;A61P3/10;A61P43/00;C07D209/14;C07D209/16;(IPC1-7):C07D209/16 主分类号 A61K9/14
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