The present invention relates to a method for preparing a chiral ester and more particularly, the method for preparing an optically pure chiral ester from an alkenyl ester at a high yield by mixing and reacting: an alkenyl ester; a ruthenium complex to activate reduction reaction of said alkenyl ester and racemization; a lipase to acylate selectively one of enantiomers of said alkenyl ester; and a reducing agent to supply a hydride to said ruthenium complex. Said optically pure chiral ester of the present invention can be prepared by one-step synthesis from various types of alkenyl esters at a high yield.
申请公布号
WO0140157(A1)
申请公布日期
2001.06.07
申请号
WO2000KR01169
申请日期
2000.10.18
申请人
SAMSUNG FINE CHEMICALS CO., LTD.;POHANG UNIVERSITY OF SCIENCE AND TECHNOLOGY;PARK, JAI WOOK;KIM, MAHN-JOO;KOH, JEONG HWAN;JUNG, HYUN MIN
发明人
PARK, JAI WOOK;KIM, MAHN-JOO;KOH, JEONG HWAN;JUNG, HYUN MIN