发明名称 |
PDGF receptor kinase inhibitory compounds, their preparation, purification and pharmaceutical compositions including same |
摘要 |
An isometric enriched tyrphostin of a general formula:wherein, for Compound I, the tyrphostin is enriched either for R6 at position 6 or for R6 at position 7, or, for Compound II, the tyrphostin is enriched either for R6 at position 6 or for R6 at position 8. Further disclosed are pharmaceutical compositons containing the isometric enriched tyrphostin and methods of using same to treat cell proliferative diseases. |
申请公布号 |
AU1173001(A) |
申请公布日期 |
2001.06.06 |
申请号 |
AU20010011730 |
申请日期 |
2000.11.02 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF |
发明人 |
ALEXANDER LEVITZKI;AVIV GAZIT;SHMUEL BANAI;DAVID S. GERTZ;GERSHON GOLOMB;FRANK D. BOEHMER;JOHANNES WALTENBERGER |
分类号 |
A61K31/4985;A61K47/34;A61P1/16;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P35/02;A61P37/06;A61P43/00;C07D487/04 |
主分类号 |
A61K31/4985 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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