发明名称 |
Methods for generating and screening novel metabolic pathways |
摘要 |
The present invention relates to a novel drug discovery system for generating molecular diversity. The system provides methods for subjecting the genetic materials from a plurality of species of organisms to homologous or homeologous recombination to create novel genes and metabolic pathways. The recombined genetic materials are cloned to form recombined combinatorial gene expression libraries. Methods for screening such gene expression libraries containing recombined genes and metabolic pathways for novel activities and compounds are also provided.
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申请公布号 |
US6242211(B1) |
申请公布日期 |
2001.06.05 |
申请号 |
US19990263352 |
申请日期 |
1999.03.05 |
申请人 |
TERRAGEN DISCOVERY, INC. |
发明人 |
PETERSON TODD C.;BRIAN PAUL |
分类号 |
C12N15/09;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/10;C12N15/12;C12N15/31;C12N15/66;C12P21/02;C12Q1/02;C12Q1/68;(IPC1-7):C12N15/66;C12N15/90;C12N15/70;C12N15/85 |
主分类号 |
C12N15/09 |
代理机构 |
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