| 摘要 |
The present invention provides vaccines and methods for making the vaccines that actively or passively protect a human or animal against <i>Chlamydia</i> infection. In particular, the present invention provides a vaccine that provides active immunity which comprises a polypeptide or DNA vaccine that contains or expresses at least one epitope of polypeptide that has an amino acid sequence that is substantially similar to an amino acid sequence of a polypeptide encoded by open reading frame CT863 of <i>Chlamydia trachomatis</i>. The present invention further provides a vaccine that provides passive immunity to <i>Chlamydia</i> comprising polyclonal or monoclonal antibodies against at least one epitope of a polypeptide encoded by open reading frame CT863 of <i>Chlamydia trachomatis</i>. Further still, the present invention provides a method for preventing an inflammatory reaction, in particular, in a skin graft, by providing a polypeptide that is substantially similar to a polypeptide encoded by open reading frame CT863 of <i>Chlamydia trachomatis</i>. |
