发明名称 |
ULTRAVIOLET IRRADIATION APPARATUS FOR PHOTOCHEMICAL REACTION AND METHOD FOR PREPARING VITAMIN D DERIVATIVE USING THE SAME |
摘要 |
<p>Disclosed herein are an ultraviolet irradiation apparatus for photochemical reactions which can irradiate the photo-reactive solution with ultraviolet rays having a specific wavelength suitable for the intended photochemical reaction at a high efficiency, and a process by which a provitamin D derivative can be converted into a previtamin D derivative at a high efficiency by means of a photochemical reaction by one-step process of light irradiation, thereby preparing a vitamin D derivative at a high efficiency. The ultraviolet irradiation apparatus irradiates the photo-reactive solution with the ultraviolet rays having the specific wavelength through a quartz rod. Specifically, the apparatus is constructed by an electric discharge lamp, a condensing and reflecting mirror and a plane mirror both having wavelength selective property, an optical filter which transmits the ultraviolet rays having the specific wavelength, and a quartz rod on which the ultraviolet rays having the specific wavelength are struck. The photo-reactive solution is irradiated with the ultraviolet rays from the quartz rod. The quartz rod is immersed in the photo-reactive solution, or a reaction vessel is irradiated with the ultraviolet rays from the quartz rod. In the preparation process of the vitamin D derivative, an ultraviolet irradiation apparatus for photochemical reactions having an ultraviolet radiation-emitting lamp, an optical system having wavelength selective property and a quartz rod on which the ultraviolet rays having the specific wavelength from the optical system are struck is used, and a solution of a provitamin D derivative is irradiated with the ultraviolet rays having the specific wavelength emitted from the quartz rod to cause a photochemical reaction of the provitamin D derivative solution, thereby forming a previtamin D derivative. The previtamin D derivative is further subjected to a thermal isomerization reaction to prepare the vitamin D derivative. <IMAGE></p> |
申请公布号 |
EP1103300(A1) |
申请公布日期 |
2001.05.30 |
申请号 |
EP19990959113 |
申请日期 |
1999.06.29 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
MICHISHITA, TADAO;WATANABE, SATOSHI;KATOH, MASAHIRO;MIKAMI, TETSUHIRO;TSUZAKI, KANAME;OIKAWA, KOJI;UEHARA, MAKOTO |
分类号 |
B01J19/12;C07C401/00;(IPC1-7):B01J19/12 |
主分类号 |
B01J19/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|