Compositions for transdermal and transmucosal administration of therapeutic agents

摘要

A composition for transdermal or transmucosal administration of a therapeutic agent is described. Penetration of the agent across the skin or mucosa is achieved in the presence of an acylated amino acid selected to enhance the agent to be administered. In some embodiments, a liposomal carrier vehicle is included in the composition. Also disclosed are methods for administration and for selection of an acylated amino acid to optimize transdermal or transmucosal administration of a selected agent.