发明名称 |
GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE |
摘要 |
A means and method for increasing or inhibiting the secretion of cytokines using gallotannins and ellagitannins is described. The preferred cytokine release inhibiting compounds are dimeric gallotannins having a linker molecule that misaligns the carbohydrate cores of the compounds. The preferred cytokine release promoting gallotannins and ellagitannins include a diaryl ether linker unit. In comparison to the more structurally complex ellagitannins, the compounds of this invention are structurally simpler, easier to synthesize, and more potent. |
申请公布号 |
WO0136436(A1) |
申请公布日期 |
2001.05.25 |
申请号 |
WO2000US31648 |
申请日期 |
2000.11.17 |
申请人 |
THE PENN STATE RESEARCH FOUNDATION;FELDMAN, KENNETH, S. |
发明人 |
FELDMAN, KENNETH, S. |
分类号 |
A61K31/7024;A61P31/04;A61P43/00;C07H13/08 |
主分类号 |
A61K31/7024 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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