摘要 |
<p>Thiamin disulfide derivatives represented by general formula (1) or salts thereof and drugs containing the same as the active ingredient, wherein X?1 and X2¿ are the same or different and each represents hydrogen or halogeno; and R1 represents linear or branched alkylene. The compounds (1) or salts thereof are free from the problem of hardly water-soluble properties, which is a shortcoming of the conventional thiamin disulfides, and has a potent anti-HIV activity, thereby being useful as remedies for HIV-infection, in particular, remedies for AIDS.</p> |