COMBINATORIAL AND AUTOMATIC DETECTION METHOD OF TARGET GENE, AND A DETECTOR USING THE METHOD

摘要

The present invention is directed to a combinatorial and automatic detection method of target gene, and a detector based on the method. Quartz Crystal Microbalance (QCM) technology in conjunction with gene chip technology is mainly used in the present invention to detect DNA; in a specific method, microfabricating technology is used to etch super-thin quartz resonator array directly on a piezoelectric quartz crystal, then, a number of probes are immobilized, so, a number of DNA or RNA molecule can be detected and analyzed simultaneously. Compared with traditional nucleic acid blot hybridization technique which shortcoming is complex, low automatic degree, less target molecule to be detected; the automatic detection method of target gene and the detector according to present invention can detect in situ without label and obtain detecting information at any time, the detector itself is so small to be carried and can be used conveniently.