发明名称 |
PHARMACEUTICAL FORMULATIONS COMPRISING LABDANES FOR THE TREATMENT OF TUMORS OR LEUKEMIAS |
摘要 |
The present invention relates to novel compositions based on hydrated lipidic lamellar phases or liposomal compositions, prepared by combining different lipid molecules, synthetic and/or from natural sources, said compositions comprising at least one of a) labd-13-ene-8 alpha , 15-diol and/or derivatives thereof; b) labd-14-ene-8, 13-diol or derivatives thereof; c) 3 beta -hydroxy-labd-14-ene-8, 13-epoxy and/or derivatives thereof; d) a plant extract containing the aforementioned labdenes or derivatives thereof. The compositions of the invention exhibit cytotoxicity against cancerous cells and are utilized for the treatment of tumors and leukemias.
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申请公布号 |
WO0134116(A2) |
申请公布日期 |
2001.05.17 |
申请号 |
WO2000GR00033 |
申请日期 |
2000.11.08 |
申请人 |
P.N. GEROLYMATOS S.A. |
发明人 |
DEMETZOS, CONSTANTINOS;DIMAS, CONSTANTINOS;ANGELOPOULOU, DEMETRA;ANASTASSAKI, THALIA;KOKKINOPOULOS, DEMETRIOS |
分类号 |
C07D311/92;A61K9/127;A61K9/133;A61K31/047;A61K31/22;A61K31/352;A61P35/00;A61P35/02;(IPC1-7):A61K9/127;A61K35/78;A61K31/222;A61K31/045 |
主分类号 |
C07D311/92 |
代理机构 |
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代理人 |
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地址 |
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