发明名称 |
COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER |
摘要 |
Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prosta te- specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.</SD OAB>
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申请公布号 |
CA2391369(A1) |
申请公布日期 |
2001.05.17 |
申请号 |
CA20002391369 |
申请日期 |
2000.11.09 |
申请人 |
CORIXA CORPORATION |
发明人 |
RETTER, MARC W.;WANG, AIJUN;STOLK, JOHN A.;SKEIKY, YASIR A.W.;DAY, CRAIG H.;KALOS, MICHAEL D.;REED, STEVEN G.;JIANG, YUQIU;HARLOCKER, SUSAN L.;MITCHAM, JENNIFER L.;DILLON, DAVIN C.;XU, JIANGCHUN |
分类号 |
G01N33/53;A61K31/711;A61K38/00;A61K39/00;A61K39/395;A61K48/00;A61P35/00;A61P35/04;C07K14/11;C07K14/47;C07K16/18;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N9/64;C12N15/09;C12N15/12;C12P21/08;C12Q1/68;G01N33/566;G01N33/574;G01N33/577;(IPC1-7):C12N15/12;C12N15/11;A61K38/17;C12N15/62;G01N33/68;A61K31/70 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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