| 摘要 |
The present invention relates to methods for the production in vitro of cell growth supportive surfaces comprising naturally secreted human extracellular matrix material comprising biologically active agents such as growth factors ideally produced and elaborated by the extracellular matrix-secreting cells. The present invention provides an efficient method for improving growth factor potency and extending half-life in order to promote cell attachment, growth and/or differentiation. The surfaces of the present invention enable propagation of difficult cells in culture.
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