| 摘要 |
PROBLEM TO BE SOLVED: To obtain a labeled compound relatively easy to synthesize, and suitable for elucidating the in vivo kinetics, mechanism of various physiological activities, etc., of a flavan-3-ol compound partly because an isotope used as a label is hard to be eliminable. SOLUTION: This compound is a flavan-3-ol compound labeled with deuterium or tritium on the 4-position and shown by the general formula (1) (wherein, R1 is H or an acyl; R2 is deuterium or tritium; R3 to R7 are each H or OH; and the steric configurations of the 2- and 3-positions of the benzopyran ring may be R- or S-configuration, respectively).
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